Endocrine Abstracts

Introduction: Normocalcemic Primary Hyperparathyroidism is today considered a variant of Primary Hyperparathyroidism. It is characterized by persistently normal calcium levels and increased levels of parathyroid hormone, after the exclusion of other causes of secondary hyperparathyroidism. We aimed to compare clinical, biochemical and imaging data from patients with normocalcemic and hypercalcemic primary hyperparathyroidism. Methods: This is a retrospec...

Introduction: Inflammatory bowel disease (IBD) has been associated with various disorders of thyroid function. Many of these patients are now treated with biological agents targeting on TNF-a.Aim: To investigate thyroid function in patients with IBD and the potential effect of anti-TNF therapy.Patients and methods: We studied 41 patients with IBD (25M/16F, 36.4±11 years), without any known thyroid disorder. Eighteen patients (...

Background & aims: Impaired glucose tolerance and diabetes as well as cardiac dysfunction are known complications in homozygous beta-thalassemic transfused patients due to iron overload. We aimed to study pancreatic alpha and beta-cell function in regularly transfused patients with homozygous beta-thalassemia and to investigate if cardiac dysfunction may correlate with the development of impaired glucose metabolism.Methods: An oral glucose tolerance ...

Introduction: The aim of this study was to investigate the degree of atherosclerosis in women of reproductive age with type 2 diabetes mellitus (T2DM), with and without polycystic ovary syndrome (PCOS).Patients and Methods: 71 women (mean age 43.2 y) with T2DM treated with diet or oral anti-diabetic medications and 36 controls were studied. According to menstrual cycle and clinical hyperandrogenism, patients with T2DM were classified into two subgroups, ...

Introduction: Polycystic ovary syndrome (PCOS) is usually accompanied by abdominal obesity and insulin resistance which are related with low-grade chronic inflammation, as evidenced by elevation of multiple markers of inflammation, among which is oxidative stress. However, as far as oxidative stress presence, the existing data are limited. The purpose of this study was the investigation of several oxidative stress markers in women with PCOS without insulin resistance.<p cl...